The overall combination is presented of six standard model (SM) Higgs boson searches performed by the CMS Collaboration using the following Higgs boson decay signatures: , , , , , and . Depending on the analysis, the amount of data used corresponds to 1.0-1.1~fb of integrated luminosity. The conclusion of this combination is that the SM Higgs boson is excluded at 95\% C.L. in two mass ranges 149-206 and 300-440~GeV/, as well as several narrower intervals in between. The expected exclusion in the absence of a signal is 127-420~GeV/. At 90\% C.L., we exclude the SM Higgs boson in the mass range from 145-480~GeV/. The same experimental search results, reinterpreted in the context of the standard model with 4 fermion generations (SM4), allow us to exclude the SM4 Higgs boson with a mass in the range 120-600 GeV/ at 95\% C.L.