Three searches are presented for signatures of physics beyond the standard model (SM) in final states in proton-proton collisions at the LHC, using a data sample collected with the CMS detector at 13 TeV, corresponding to an integrated luminosity of 138 fb. Upper limits at 95% confidence level (CL) are set on the products of the branching fraction for the decay into leptons and the cross sections for the production of a new boson , in addition to the H(125) boson, via gluon fusion (gg) or in association with b quarks, ranging from (10 pb) for a mass of 60 GeV to 0.3 fb for a mass of 3.5 TeV each. The data reveal two excesses for gg production with local -values equivalent to about three standard deviations at 0.1 and 1.2 TeV. In a search for -channel exchange of a vector leptoquark U, 95% CL upper limits are set on the dimensionless U leptoquark coupling to quarks and leptons ranging from 1 for a mass of 1 TeV to 6 for a mass of 5 TeV, depending on the scenario. In the interpretations of the and {M_{\mathrm{h},\,\text{EFT}}^{125}} minimal supersymmetric SM benchmark scenarios, additional Higgs bosons with masses below 350 GeV are excluded at 95% CL.