This note reports studies of Higgs boson production with sizeable transverse momentum decaying to a quark pair. The analyzed data were recorded with the ATLAS detector in proton-proton collisions with a center-of-mass energy of ~TeV at the Large Hadron Collider between 2015 and 2018, corresponding to an integrated luminosity of 136~fb. Higgs bosons decaying to are reconstructed as single large-radius jets and identified by the experimental signature of two -hadron decays. The experimental techniques are validated in the same kinematic regime using the process. For Higgs boson production at transverse momenta above 450 GeV, the production cross section is found to be 13\pm 57 \text{(stat.)} \pm 22 \text{(syst.)} \pm 3 \text{(theo.)} \mathrm{~fb}. The differential cross section 95% confidence level upper limits as a function of Higgs boson transverse momentum are \sigma_{H}(300< p_{\text{T}}^{H}<450~\mathrm{~GeV}) < 2.8~\mathrm{~pb}, \sigma_{H}(450< p_{\text{T}}^{H}<650~\mathrm{~GeV}) < 91~\mathrm{~fb}, \sigma_{H}(p_{\text{T}}^{H}>650~\mathrm{~GeV}) < 40.5~\mathrm{~fb}, and \sigma_{H}(p_{\text{T}}^{H}>1~\mathrm{~TeV}) < 10.3~\mathrm{~fb}. All results are consistent with the Standard Model predictions.